As part of Ohio Sinus Institute’s mission to incorporate the latest treatment options for our patients we frequently participate in or initiate institutional review board approved research protocols. This allows us to keep abreast of current clinical trends while also contributing new ideas for surgical and medical management of chronic rhinosinusitis. Some of Dr. Karanfilov’s studies are listed below.
Medical Management Protocols
1. Comparison of Balloon Sinus Dilation (Balloon Sinuplasty) for medically refractory chronic rhinosinusitis versus Maximal Medical Therapy for Chronic Rhinosinusitis.
Patients with diagnosed chronic rhinosinusitis had the option of managing their disease with a balloon sinus dilation intervention versus the second option of undergoing further medical therapy. Dr. Karanfilov served as a co-principal investigator with Dr. Chris Melroy and Dr. Spencer Payne. This study is currently closed.
2. A novel, herbal based nasal spray for nasal obstruction.
Principal investigator, Frederick A. Kuhn, M.D., of Georgia Nasal & Sinus Institute headed up a double blinded, placebo control trial evaluating the effectiveness of an all natural, herbal based nasal spray in relieving nasal obstruction. The study involved completing a few simple nasal questionnaires and taking a smell test. This study is closed.
3. A novel irrigation protocol.
A new irrigation device and irrigation formula was tested. Participants received the device and materials at no cost. Study is closed.